SCHEMBL4631471

SCHEMBL4631471

O=C(Oc1ccccc1)C1CC1C(=O)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
ELANE P08246 2/20 0.50
SLC6A3 Q01959 1/20 0.50
TDP1 Q9NUW8 2/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CHRNA7 P36544 1/20 0.42
HTR3A P46098 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3172897 0.93 ELANE (0.53) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL15731532 0.88 SLC6A3 (0.49) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL7863531 0.88 ALDH1A1 (0.50) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL15719798 0.88 SLC6A3 (0.49) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL3176400 0.85 SMN1; SMN2 (0.57) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL31321921 0.85 ALDH1A1 (0.47) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL3174235 0.85 ALDH1A1 (0.54) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL472094 0.85 ALDH1A1 (0.47) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL22655248 0.85 ALDH1A1 (0.50) ALDH1A1ELANESLC6A3TDP1HTT
SCHEMBL3175349 0.84 ELANE (0.58) ALDH1A1ELANESLC6A3TDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP disclosed
EP-1472302-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2004-11-03 EP disclosed
WO-2002046272-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2002-06-13 WO disclosed