SCHEMBL4631666

SCHEMBL4631666

C=Cc1ccccc1CSCc1ccccc1C=C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.43
CYP2C9 P11712 3/20 0.43
CYP2C19 P33261 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.35
THRB P10828 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 2/20 0.34
CYP2D6 P10635 1/20 0.34
ACHE P22303 1/20 0.34
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.30
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4200752 0.90 CYP2C19 (0.38) CYP1A2CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL14732602 0.88 ALDH1A1 (0.38) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL9067798 0.85 ALDH1A1 (0.35) CYP1A2CYP2C9CYP2C19ALDH1A1CYP2D6
SCHEMBL11424798 0.85 CYP1A2 (0.37) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL14732601 0.85 CYP1A2 (0.36) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL7206071 0.83 ALDH1A1 (0.40) ALDH1A1MEN1THRBKMT2ALMNA
SCHEMBL28175958 0.82 KDM4E (0.40) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL19539346 0.79 ALDH1A1 (0.41) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL6888749 0.79 ALDH1A1 (0.38) CYP1A2ALDH1A1MEN1THRBKMT2A
SCHEMBL11520650 0.79 RIPK1 (0.40) CYP1A2CYP2C9CYP2C19ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609061-B1 Polymerizable composition, polymer, organic glass and ophthalmic lens TOKUYAMA CORP (JP) 1999-09-29 EP claimed
US-5475074-A Copolamerizable monomers containing vinyl benzyl compound, 2,4-diphenyl-4-methyl-1-pentene and an acrylic momomer; also contains mercapto, hindered phenol and azo compounds; high refractive index, heat and radiation resistance TOKUYAMA CORPORATION (JP) 1995-12-12 US claimed
EP-0609061-A2 Polymerizable composition, polymer, organic glass and ophthalmic lens TOKUYAMA CORPORATION (JP) 1994-08-03 EP claimed
JP-3184950-A None JP disclosed
WO-2017185324-A1 GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN OLEFIN DISPROPORTIONATION REACTIONS XIA, LING (CN) 2017-11-02 WO disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1448686-A4 STABILIZED IMAGEABLE COATING COMPOSITION AND PRINTING PLATE PRECURSOR KODAK POLYCHROME GRAPHICS LLC (US) 2005-08-31 EP disclosed
US-6832554-B2 applying to cylinder, imageable coating comprising copolymer of methyl methacrylate, trimethylammoniummethyl methacrylic chloride, and N-(3-aminopropyl)methacrylamide hydrochloride, which changes affinity for printing fluid upon infrared exposure KODAK POLYCHROME GRAPHICS LLC 2004-12-21 US disclosed
EP-1448686-A1 STABILIZED IMAGEABLE COATING COMPOSITION AND PRINTING PLATE PRECURSOR Kodak Polychrome Graphics LLC (US) 2004-08-25 EP disclosed
EP-1093417-A4 PROCESSLESS DIRECT WRITE IMAGING MEMBER CONTAINING POLYMER GRAFTED CARBON AND METHODS OF IMAGING AND PRINTING KODAK POLYCHROME GRAPHICS CO (US) 2004-07-14 EP disclosed
US-6762223-B2 CARBON PIGMENT DISPERSIBLE IN WATER; POLYMER COMPRISING AT LEAST ONE IONOMERIC POLYMER SUBUNIT; AND AT LEAST ONE HIGH MOLECULAR WEIGHT THICKENING AGENT WHICH SHOWS PSEUDOPLASTIC BEHAVIOR. KODAK POLYCHROME GRAPHICS LLC 2004-07-13 US disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-6190830-B1 UNITS CONTAINING AN ORGANOAMMONIUM, ORGANOPHOSPHONIUM OR ORGANOSULFONIUM GROUP THAT REACTS TO PROVIDE INCREASED OLEOPHILICITY (INK RECEPTIVITY) IN RESPONSE TO HEAT. KODAK POLYCHROME GRAPHICS LLC 2001-02-20 US disclosed
US-6159657-A Thermal imaging composition and member containing sulfonated ir dye and methods of imaging and printing EASTMAN KODAK COMPANY (US) 2000-12-12 US disclosed
WO-2000063025-A1 PROCESSLESS DIRECT WRITE IMAGING MEMBER CONTAINING POLYMER GRAFTED CARBON AND METHODS OF IMAGING AND PRINTING KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2000-10-26 WO disclosed
EP-0990516-A1 Processless direct write printing plate and methods of imaging and printing Kodak Polychrome Graphics LLC (US) 2000-04-05 EP disclosed
EP-0609061-B1 Polymerizable composition, polymer, organic glass and ophthalmic lens TOKUYAMA CORP (JP) 1999-09-29 EP disclosed
US-5475074-A Copolamerizable monomers containing vinyl benzyl compound, 2,4-diphenyl-4-methyl-1-pentene and an acrylic momomer; also contains mercapto, hindered phenol and azo compounds; high refractive index, heat and radiation resistance TOKUYAMA CORPORATION (JP) 1995-12-12 US disclosed
EP-0609061-A2 Polymerizable composition, polymer, organic glass and ophthalmic lens TOKUYAMA CORPORATION (JP) 1994-08-03 EP disclosed
JP-H03184950-A NEW ORGANOSULFUR COMPOUND, ITS PRODUCTION AND RESIN FOR OPTICAL USE THEREFROM NIPPON OIL & FATS CO LTD 1991-08-12 JP disclosed