Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | FNTA | P49354 | 1/20 | 0.63 |
| ▸ | FNTB | P49356 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MPO | P05164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717728 | 0.85 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL2269865 | 0.85 | MAPT (0.69) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL40822 | 0.85 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29376364 | 0.85 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3262116 | 0.85 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4598405 | 0.83 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30295582 | 0.83 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL26344 | 0.83 | MEN1 (0.75) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL29350750 | 0.83 | MEN1 (0.75) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL7887240 | 0.83 | MEN1 (0.75) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |