Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 7/20 | 0.43 |
| ▸ | GART | P22102 | 3/20 | 0.43 |
| ▸ | ATIC | P31939 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801459 | 0.97 | TYMS (0.62) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801452 | 0.97 | TYMS (0.62) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL463710 | 0.95 | TYMS (0.54) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801454 | 0.92 | TYMS (0.58) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801450 | 0.91 | TYMS (0.69) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL463153 | 0.91 | TYMS (0.69) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL16587653 | 0.87 | TYMS (0.67) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL18709115 | 0.87 | TYMS (0.67) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801317 | 0.86 | TYMS (0.74) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801597 | 0.86 | TYMS (0.63) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8986650-B2 | Complex folate-NOTA-Ga68 | GUERBET (FR) | 2015-03-24 | — | — | US | disclosed |
| US-8926945-B2 | Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium | GUERBET (FR) | 2015-01-06 | — | — | US | disclosed |
| US-20120064003-A1 | COMPLEX FOLATE-NOTA-Ga68 | GUERBET (FR) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064003-A1 | COMPLEX FOLATE-NOTA-Ga68 | FOLR1, FOLR2, DHFR | TYMS 26/4885KDM4E 4207/4885MEN1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.