SCHEMBL463194

SCHEMBL463194

C=CCC(CCC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 12/20 0.56
GRIK1 P39086 2/20 0.52
GRIK2 Q13002 2/20 0.52
CPA1 P15085 1/20 0.50
GRM3 Q14832 2/20 0.48
NAALAD2 Q9Y3Q0 1/20 0.48
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
BLM P54132 1/20 0.47
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8805759 0.98 FOLH1 (0.54) FOLH1GRIK1GRIK2CPA1GRM3
SCHEMBL7752392 0.88 FOLH1 (0.52) FOLH1GRIK1GRIK2CPA1SLC6A2
SCHEMBL11795592 0.88 ABCC4 (0.50) FOLH1GRIK1GRIK2CPA1SLC6A2
SCHEMBL11802696 0.86 ABCC4 (0.53) FOLH1GRIK1GRIK2CPA1SLC6A2
SCHEMBL30458073 0.86 ABCC4 (0.53) FOLH1GRIK1GRIK2CPA1SLC6A2
SCHEMBL11796940 0.86 ABCC4 (0.53) FOLH1GRIK1GRIK2CPA1SLC6A2
SCHEMBL11784979 0.86 ABCC4 (0.53) FOLH1GRIK1GRIK2CPA1SLC6A2
SCHEMBL9376537 0.83 GRIK1 (0.53) FOLH1GRIK1GRIK2CPA1GRM3
SCHEMBL891727 0.81 GRIK1 (0.64) FOLH1GRIK1GRIK2CPA1SLC6A3
SCHEMBL8031351 0.80 GRIK1 (0.53) FOLH1GRIK1GRIK2CPA1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209697-A Polyester containing biomass-derived components and method for producing same 可隆工业株式会社 2023-06-02 CN claimed
EP-1734936-B1 AMPHIPHILIC STAR-LIKE OR SCOPRION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF UNIV RUTGERS (US) 2014-09-10 EP claimed
US-20120039983-A1 AMPHIPHILIC MACROMOLECULE-LIPID COMPLEXES UHRICH KATHRYN E (US) 2012-02-16 US claimed
US-20120022159-A1 AMPHIPHILIC STAR-LIKE OR SCORPION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF UHRICH KATHRYN E (US) 2012-01-26 US claimed
US-20110229416-A1 AMPHIPHILIC MACROMOLECULES FOR SOLUBILIZING NANOCRYSTALS VANDERBILT UNIVERSITY 2011-09-22 US claimed
US-20110008396-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR CONDITIONS RUTGERS, THE SATE UNIVERSITY OF NEW JERSEY (US) 2011-01-13 US claimed
US-20090175932-A1 MICELLE ASSEMBLIES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2009-07-09 US claimed
WO-2009039505-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR CONDITIONS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2009-03-26 WO claimed
US-20080057026-A1 Amphiphilic Star-Like Or Scorpion-Like Macromolecules, Various Compositions And Uses Threof RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2008-03-06 US claimed
EP-1734936-A2 AMPHIPHILIC STAR-LIKE OR SCOPRION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF Rutgers, The State University (US) 2006-12-27 EP claimed
EP-1531835-A4 MICELLE ASSEMBLIES UNIV RUTGERS (US) 2006-12-13 EP claimed
US-20060039964-A1 Micelle assemblies RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2006-02-23 US claimed
WO-2005074887-A2 AMPHIPHILIC STAR-LIKE OR SCORPION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF RUTGERS, THE STATE UNIVERSITY (US) 2005-08-18 WO claimed
EP-1531835-A2 MICELLE ASSEMBLIES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2005-05-25 EP claimed
WO-2003103594-A2 MICELLE ASSEMBLIES RUTGERS, THE STATE UNIVERSITY (US) 2003-12-18 WO claimed
US-3981780-A CYCLIC AMINES, SALT OF DICARBOXYLIC ACID AND ALIPHATIC AMINE COMPAGNIE FRANCAISE DE RAFFINAGE (FR) 1976-09-21 US claimed
CN-113195655-B Process for producing functionalized polyesters 汉高股份有限及两合公司 2023-05-12 CN disclosed
EP-3670618-B1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS HENKEL AG & CO KGAA (DE) 2023-05-03 EP disclosed
US-3981780-A CYCLIC AMINES, SALT OF DICARBOXYLIC ACID AND ALIPHATIC AMINE COMPAGNIE FRANCAISE DE RAFFINAGE (FR) 1976-09-21 US disclosed
US-3979309-A Lubricating oil additive UOP INC. (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110229416-A1 AMPHIPHILIC MACROMOLECULES FOR SOLUBILIZING NANOCRYSTALS ANXA2, ANXA6, ANXA1 FOLH1 2009/4885GRIK1 4800/4885GRIK2 4644/4885
US-20120022159-A1 AMPHIPHILIC STAR-LIKE OR SCORPION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF STARD3, CETP, MSR1 FOLH1 2902/4885GRIK1 3635/4885GRIK2 3933/4885
US-20120039983-A1 AMPHIPHILIC MACROMOLECULE-LIPID COMPLEXES APOB, APOL1, CETP FOLH1 2521/4885GRIK1 2066/4885GRIK2 1825/4885
US-20080057026-A1 Amphiphilic Star-Like Or Scorpion-Like Macromolecules, Various Compositions And Uses Threof CETP, STARD3, MSR1 FOLH1 1570/4885GRIK1 3807/4885GRIK2 3802/4885
US-20110008396-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR CONDITIONS APOB, FABP3, LIPA FOLH1 982/4885GRIK1 4396/4885GRIK2 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.