SCHEMBL4632137

SCHEMBL4632137

C=CC(=O)OCC(O)CN1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.52
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ATM Q13315 2/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP2D6 P10635 2/20 0.46
CYP2C19 P33261 1/20 0.46
ABCB1 P08183 10/20 0.46
TSHR P16473 2/20 0.44
HIF1A Q16665 1/20 0.44
ACE2 Q9BYF1 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28123602 0.78 PKM (0.56) PKMMEN1KMT2AATMHSD17B10
SCHEMBL761032 0.78 PKM (0.56) PKMMEN1KMT2AATMHSD17B10
SCHEMBL95157 0.76 TSHR (0.64) HSD17B10TSHRHIF1AMAPT
SCHEMBL4187283 0.76 TSHR (0.43) PKMHSD17B10TSHRHIF1A
SCHEMBL6569639 0.76 PKM (0.51) PKMMEN1KMT2AATMHSD17B10
SCHEMBL13051008 0.75 TSHR (0.42) MEN1KMT2AHSD17B10TSHRHIF1A
SCHEMBL11297066 0.73 TSHR (0.47) HSD17B10TSHRHIF1A
SCHEMBL13051009 0.73 TSHR (0.43) MEN1KMT2AHSD17B10TSHRHIF1A
SCHEMBL11355209 0.73 TSHR (0.44) PKMKMT2AHSD17B10CYP2D6CYP2C19
SCHEMBL69499 0.73 TSHR (0.48) MEN1KMT2AHSD17B10TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-0752612-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2004-04-21 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-0764506-B1 PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES ARACO KK (JP) 2002-01-02 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-6024895-A COMPRISING SOLUBLE, ELECTRICALLY CONDUCTING POLYMER HAVING SULFONIC ACID GROUP AND/OR CARBOXYL GROUP AND THERMALLY CROSS-LINKABLE OR ULTRAVIOLET- OR ELECTRON BEAM-CROSS-LINKABLE RESIN OR PAINT MITSUBISHI RAYON CO., LTD. (JP) 2000-02-15 US disclosed
US-5961902-A Manufacturing method for molded multilayer article ARACO KABUSHIKI KAISHA (JP) 1999-10-05 US disclosed
US-5859722-A Electrochromic device NIPPOM OIL CO., LTD (JP) 1999-01-12 US disclosed
EP-0844284-A1 CROSS-LINKABLE CONDUCTIVE COMPOSITION, CONDUCTOR, AND PROCESS FOR FORMING THE SAME NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1998-05-27 EP disclosed
EP-0837112-A2 Cross-linkable, electrically conductive composition, electric conductor and process for forming the same NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1998-04-22 EP disclosed
EP-0764506-A1 PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES ARACO KABUSHIKI KAISHA (JP) 1997-03-26 EP disclosed
EP-0752612-A1 Electrochromic device NIPPON OIL CO., LTD. (JP) 1997-01-08 EP disclosed