SCHEMBL4632149

SCHEMBL4632149

OC/C(F)=C/c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
AKR1C3 P42330 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
AKR1C1 Q04828 1/20 0.39
ESR1 P03372 1/20 0.39
RECQL P46063 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
FBP1 P09467 3/20 0.36
NR1I2 O75469 1/20 0.36
PRMT1 Q99873 1/20 0.35
LMNA P02545 1/20 0.35
KDM1A O60341 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632150 1.00 ALDH1A1 (0.40) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL9433556 1.00 ALDH1A1 (0.40) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL14416291 0.84 KDM1A (0.46) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL256695 0.84 KDM1A (0.46) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL9310823 0.84 KDM1A (0.46) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL9260971 0.79 AKR1C3 (0.43) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL6725291 0.79 MAOB (0.40) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL9260964 0.79 AKR1C3 (0.43) ALDH1A1TSHRAKR1C3CYP3A4CYP2C9
SCHEMBL1689623 0.77 TRPA1 (0.41) ALDH1A1CYP2C9FBP1
SCHEMBL1689625 0.77 TRPA1 (0.41) ALDH1A1CYP2C9FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-6191184-B1 SUITABLE FOR FORMATION OF LIQUID CRYSTAL DISPLAY (LCD) SPACERS OR PROTECTIVE LAYERS; PHOTOSETTING PROPERTIES ADHESIVENESS TO SUBSTRATES; MECHANICAL CHARACTERISTICS, STORAGE STABILITY SHOW EXCELLENT WORKING FUJI PHOTO FILM CO., LTD. (JP) 2001-02-20 US disclosed
US-5276150-A Vasodilators, anticoagulants, calcium channel blockers FUJIREBIO INC. (JP) 1994-01-04 US disclosed
EP-0400660-A1 1,4-dihydropyridine derivatives FUJIREBIO INC. (JP) 1990-12-05 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed
US-4267359-A Novel carboxylic acid esters ZOECON CORPORATION (US) 1981-05-12 US disclosed
US-4204071-A 4-Aryl-3-butenoic acids and lower alkyl esters ZOECON CORPORATION (US) 1980-05-20 US disclosed