Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399348 | 0.90 | IDO1 (0.60) | CHRNB2CHRNA7CHRNA4IFNAR1IDO1 | |
| SCHEMBL3192924 | 0.86 | IFNAR1 (0.50) | IFNAR1IDO1SLC6A2SLC6A4RECQL | |
| SCHEMBL3196131 | 0.85 | CHRNB2 (0.48) | CHRNB2CHRNA7CHRNA4IFNAR1IDO1 | |
| SCHEMBL736864 | 0.85 | IDO1 (0.49) | IFNAR1IDO1SLC6A2SLC6A4RECQL | |
| SCHEMBL4632786 | 0.85 | IDO1 (0.51) | IFNAR1IDO1SLC6A2SLC6A4RECQL | |
| SCHEMBL3189739 | 0.84 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4IDO1GPR84 | |
| SCHEMBL1399362 | 0.84 | IFNAR1 (0.60) | IFNAR1IDO1SLC6A2SLC6A4RECQL | |
| SCHEMBL4632657 | 0.83 | MEN1 (0.56) | IFNAR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4632770 | 0.83 | IFNAR1 (0.47) | IFNAR1SLC6A2SLC6A4RECQLLMNA | |
| SCHEMBL3186476 | 0.82 | SLC6A2 (0.58) | IFNAR1SLC6A2SLC6A4RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701940-B1 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI | LUNDBECK & CO AS H (DK) | 2008-05-28 | — | — | EP | claimed |