Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121387 | 1.00 | SIGMAR1 (0.48) | SIGMAR1KMT2AMEN1ATMDPP4 | |
| SCHEMBL147671 | 0.93 | KMT2A (0.48) | SIGMAR1KMT2AMEN1ATMDPP4 | |
| SCHEMBL147670 | 0.93 | KMT2A (0.48) | SIGMAR1KMT2AMEN1ATMDPP4 | |
| SCHEMBL147672 | 0.93 | KMT2A (0.48) | SIGMAR1KMT2AMEN1ATMDPP4 | |
| SCHEMBL1726613 | 0.92 | KMT2A (0.48) | SIGMAR1KMT2AMEN1L3MBTL1DRD2 | |
| SCHEMBL121388 | 0.92 | KMT2A (0.48) | SIGMAR1KMT2AMEN1L3MBTL1DRD2 | |
| SCHEMBL143625 | 0.85 | MC1R (0.49) | SIGMAR1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL143627 | 0.85 | MC1R (0.49) | SIGMAR1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL143626 | 0.85 | MC1R (0.49) | SIGMAR1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL19985856 | 0.84 | L3MBTL1 (0.45) | SIGMAR1KMT2AL3MBTL1TP53DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406256-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2010103335-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |