Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454149 | 0.84 | MEN1 (0.45) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL29513591 | 0.84 | KMT2A (0.56) | MEN1KMT2AALDH1A1TDP1CA1 | |
| SCHEMBL21826840 | 0.84 | KMT2A (0.56) | MEN1KMT2AALDH1A1TDP1CA1 | |
| SCHEMBL7222277 | 0.82 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL30622686 | 0.81 | MEN1 (0.45) | MEN1KMT2AALDH1A1TDP1CA1 | |
| SCHEMBL16475128 | 0.81 | MEN1 (0.45) | MEN1KMT2AALDH1A1TDP1CA1 | |
| SCHEMBL2068719 | 0.81 | MEN1 (0.45) | MEN1KMT2AALDH1A1TDP1CA1 | |
| SCHEMBL1959760 | 0.81 | MEN1 (0.45) | MEN1KMT2AALDH1A1TDP1CA1 | |
| SCHEMBL911571 | 0.81 | MEN1 (0.45) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL7372433 | 0.78 | MEN1 (0.46) | MEN1KMT2AALDH1A1TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634574-B1 | Novel black two ring heteroaromatic direct dyes | OREAL (FR) | 2008-05-28 | — | — | EP | disclosed |
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7288124-B2 | Heteroaromatic binuclear black direct dyes | L'OREAL S.A. (FR) | 2007-10-30 | — | — | US | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-20060053568-A1 | Novel heteroaromatic binuclear black direct dyes | L'OREAL S.A. (FR) | 2006-03-16 | — | — | US | disclosed |
| EP-1634574-A2 | Novel black two ring heteroaromatic direct dyes | L'OREAL (FR) | 2006-03-15 | — | — | EP | disclosed |
| US-20050081313-A1 | Novel couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1459732-A1 | Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler | L'OREAL (FR) | 2004-09-22 | — | — | EP | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060053568-A1 | Novel heteroaromatic binuclear black direct dyes | KRT18, MKI67, TUBA4A | MEN1 4099/4885KMT2A 1536/4885ALDH1A1 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.