Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 16/20 | 0.64 |
| ▸ | AR | P10275 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631780 | 0.91 | VDR (0.65) | VDRAR | |
| SCHEMBL4631782 | 0.84 | VDR (0.64) | VDRAR | |
| SCHEMBL14199190 | 0.80 | VDR (0.37) | VDRARHDAC3HDAC6 | |
| SCHEMBL7181681 | 0.80 | VDR (1.00) | VDRARHDAC3HDAC6 | |
| SCHEMBL29754394 | 0.80 | VDR (1.00) | VDRARHDAC3HDAC6 | |
| SCHEMBL4632264 | 0.78 | VDR (0.47) | VDRAR | |
| SCHEMBL4632346 | 0.76 | VDR (0.65) | VDRAR | |
| SCHEMBL3850228 | 0.76 | VDR (0.61) | VDRAR | |
| SCHEMBL16183037 | 0.75 | VDR (0.89) | VDRARHDAC3HDAC6 | |
| SCHEMBL16177773 | 0.75 | VDR (0.89) | VDRARHDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692123-B1 | PHENYL-FURAN COMPOUNDS AS VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1692123-B1 | PHENYL-FURAN COMPOUNDS AS VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-05-28 | — | — | EP | disclosed |