SCHEMBL4632346

SCHEMBL4632346

CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1oc(C(=O)N(C)C)cc1C

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
VDR P11473 17/20 0.65
AR P10275 5/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631780 0.85 VDR (0.65) VDRAR
SCHEMBL3856053 0.84 VDR (0.64) VDRAR
SCHEMBL7181681 0.80 VDR (1.00) VDRAR
SCHEMBL29754394 0.80 VDR (1.00) VDRAR
SCHEMBL16183080 0.78 VDR (0.89) VDRAR
SCHEMBL3852150 0.78 VDR (0.64) VDRAR
SCHEMBL1776852 0.78 VDR (0.70) VDRAR
SCHEMBL3851349 0.77 VDR (0.58) VDRAR
SCHEMBL4632300 0.76 VDR (0.64) VDRAR
SCHEMBL16177773 0.76 VDR (0.89) VDRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1692123-B1 PHENYL-FURAN COMPOUNDS AS VITAMIN D RECEPTOR MODULATORS LILLY CO ELI (US) 2008-05-28 EP disclosed