SCHEMBL4632318

SCHEMBL4632318

CCCCCCCCCONC(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.53
ACHE P22303 11/20 0.47
NAAA Q02083 1/20 0.47
FAAH O00519 1/20 0.43
TSHR P16473 2/20 0.43
DGKA P23743 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10773332 0.94 EPHX1 (0.44) EPHX1ACHENAAA
SCHEMBL1136659 0.92 SMN1; SMN2 (0.45) EPHX1ACHETSHR
SCHEMBL541144 0.84 GAA (0.42) EPHX1ACHE
Hydrochloric Acid SCHEMBL10556812 0.82 GAA (0.41) EPHX1ACHE
SCHEMBL6576436 0.82 EPHX1 (0.53) EPHX1ACHETSHR
SCHEMBL8516233 0.82 EPHX1 (0.48) EPHX1NAAAFAAHTSHR
SCHEMBL9490477 0.82 EPHX1 (0.48) EPHX1NAAAFAAHTSHR
SCHEMBL28294548 0.81 GAA (0.37) EPHX1ACHE
SCHEMBL252825 0.79 EPHX1 (0.45) EPHX1ACHENAAAFAAHTSHR
SCHEMBL2363599 0.79 TSHR (0.51) EPHX1ACHENAAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535939-B1 Blocked polyisocyanate BAYER MATERIALSCIENCE LLC (US) 2008-05-21 EP disclosed
EP-1535939-A1 Blocked polyisocyanate Bayer MaterialScience LLC (US) 2005-06-01 EP disclosed
US-20050113550-A1 BLOCKED POLYISOCYANATE BAYER MATERIALSCIENCE LLC 2005-05-26 US disclosed
US-6894138-B1 Blocked polyisocyanate BAYER MATERIALSCIENCE LLC (US) 2005-05-17 US disclosed