Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555587 | 0.87 | — | — | |
| SCHEMBL6832475 | 0.85 | TDP1 (0.34) | TDP1EPHX1 | |
| SCHEMBL4630334 | 0.84 | EPHX1 (0.39) | EPHX1CES2CES1 | |
| SCHEMBL1276540 | 0.80 | CES2 (0.47) | EPHX1CES2CES1 | |
| SCHEMBL1099068 | 0.79 | — | — | |
| SCHEMBL7683067 | 0.77 | TDP1 (0.36) | TDP1HDAC3HDAC1HDAC2HDAC8 | |
| Water SCHEMBL27857925 | 0.77 | — | — | |
| SCHEMBL11674646 | 0.77 | — | — | |
| SCHEMBL4631863 | 0.77 | ALDH1A1 (0.35) | TDP1 | |
| SCHEMBL18871923 | 0.75 | TDP1 (0.34) | TDP1EPHX1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716197-B1 | HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS | BASF SE (DE) | 2008-10-29 | — | — | EP | claimed |
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |