SCHEMBL4632485

SCHEMBL4632485

O=[N+]([O-])c1ccc(/C=C/C(O)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.54
BCHE P06276 1/20 0.54
PTGS2 P35354 2/20 0.50
CYP1B1 Q16678 1/20 0.50
APP P05067 1/20 0.50
FBP1 P09467 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
PTGS1 P23219 1/20 0.47
CYP19A1 P11511 1/20 0.47
MAPT P10636 3/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 2/20 0.46
ALDH1A1 P00352 1/20 0.46
NFE2L2 Q16236 1/20 0.45
SNCA P37840 1/20 0.45
MAOA P21397 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632486 1.00 MAOB (0.54) MAOBBCHEPTGS2CYP1B1APP
SCHEMBL10411854 0.83 CYP1A2 (0.52) MAOBCYP19A1LMNANFE2L2MAOA
SCHEMBL477646 0.79 CYP1A2 (0.57) MAOBSMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL477645 0.79 CYP1A2 (0.57) MAOBSMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL477467 0.79 CYP1A2 (0.57) MAOBSMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL477469 0.79 CYP1A2 (0.57) MAOBSMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL1791677 0.78 MAOB (0.48) MAOBBCHEPTGS2CYP1B1APP
SCHEMBL1405433 0.77 CYP19A1 (0.72) MAOBBCHEPTGS2CYP1B1APP
SCHEMBL29136503 0.77 CYP19A1 (0.72) MAOBBCHEPTGS2CYP1B1APP
SCHEMBL1405432 0.77 CYP19A1 (0.72) MAOBBCHEPTGS2CYP1B1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed