SCHEMBL477646

SCHEMBL477646

OC(C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.57
MAOB P27338 1/20 0.44
CYP3A4 P08684 1/20 0.43
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477645 1.00 CYP1A2 (0.57) CYP1A2MAOBCYP3A4ALDH1A1LMNA
SCHEMBL477467 1.00 CYP1A2 (0.57) CYP1A2MAOBCYP3A4ALDH1A1LMNA
SCHEMBL477469 1.00 CYP1A2 (0.57) CYP1A2MAOBCYP3A4ALDH1A1LMNA
SCHEMBL10411854 0.95 CYP1A2 (0.52) CYP1A2MAOBCYP3A4LMNACYP2C9
SCHEMBL28403553 0.88 ALOX15 (0.50) CYP1A2MAOBALDH1A1LMNAMAPT
SCHEMBL10247169 0.86 MEN1 (0.50) CYP1A2CYP3A4ALDH1A1LMNAMAPT
SCHEMBL6228450 0.86 MAPT (0.46) CYP1A2MAOBCYP3A4ALDH1A1LMNA
SCHEMBL4631562 0.86 CYP3A4 (0.47) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL4631564 0.86 CYP3A4 (0.47) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL4630867 0.86 CYP3A4 (0.51) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586468-A (R) -BNBA-TP-COF polymer and preparation method and application thereof 山东师范大学 2024-02-23 CN claimed
CN-117586468-A (R) -BNBA-TP-COF polymer and preparation method and application thereof 山东师范大学 2024-02-23 CN disclosed
CN-114315917-B Chiral ferrocene PNNO tetradentate ligand and application thereof in asymmetric hydrogenation reaction 武汉大学 2023-04-25 CN disclosed
CN-114315917-A Chiral ferrocene PNNO tetradentate ligand and application thereof in asymmetric hydrogenation reaction 武汉大学 2022-04-12 CN disclosed
EP-2775996-B1 USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS MERCK PATENT GMBH (DE) 2018-02-28 EP disclosed
US-9751081-B2 Self-regenerating antioxidant catalysts and methods of using the same CLEMSON UNIVERSITY (US) 2017-09-05 US disclosed
US-20160151773-A1 SELF-REGENERATING ANTIOXIDANT CATALYSTS AND METHODS OF USING THE SAME CLEMSON UNIVERSITY 2016-06-02 US disclosed
US-20150051295-A1 USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS MERCK PATENT GMBH (DE) 2015-02-19 US disclosed
EP-2775996-A2 USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS Merck Patent GmbH (DE) 2014-09-17 EP disclosed
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-0668860-A1 PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES PHARMACIA & UPJOHN COMPANY (US) 1995-08-30 EP disclosed
WO-1994011361-A1 PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES THE UPJOHN COMPANY (US) 1994-05-26 WO disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
EP-0046033-B1 METHOD FOR ASYMMETRIC EPOXIDATION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1986-10-15 EP disclosed
US-4594439-A Resolution of chiral carbinol having aliphatic unsaturation THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) 1986-06-10 US disclosed
US-4560811-A LEWIS ACID CATALYST, CHIRAL GLYCOL, PEROXY COMPOUNDS, OLEFINS OREPOXZIDES; INTERMEDIATES FOR DRUGS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1985-12-24 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed
US-4471130-A SELECTIVE STEREOISOMERS BY REACTING AN ALKENOL AND HYDROPEROXIDE USING A TRANSITION METAL ALKOKIDE CATALYST THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1984-09-11 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed
EP-0046033-A1 Method for asymmetric epoxidation THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1982-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051295-A1 USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS GPX4, EBP, CAT CYP1A2 292/4885MAOB 2199/4885CYP3A4 233/4885
US-20160151773-A1 SELF-REGENERATING ANTIOXIDANT CATALYSTS AND METHODS OF USING THE SAME SOD1, CAT, GPX4 CYP1A2 1495/4885MAOB 413/4885CYP3A4 1862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.