Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278005 | 0.89 | SCN9A (0.45) | KMT2AMEN1SCN9AMAPTNPSR1 | |
| SCHEMBL4667376 | 0.85 | ANO1 (0.45) | SMN1; SMN2CAPN1KMT2AMAPT | |
| SCHEMBL4837212 | 0.85 | ANO1 (0.41) | SMN1; SMN2P2RX7 | |
| SCHEMBL4632200 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2CAPN1KMT2AMEN1MAPT | |
| SCHEMBL269012 | 0.77 | PTPN1 (0.42) | SCN9A | |
| SCHEMBL269828 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2CAPN1CNR1CNR2KMT2A | |
| SCHEMBL268438 | 0.77 | SCN9A (0.40) | SMN1; SMN2SCN9AMAPT | |
| SCHEMBL277711 | 0.76 | ACE (0.43) | KMT2ASCN9AMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL268993 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2CAPN1CNR1CNR2KMT2A | |
| SCHEMBL268932 | 0.76 | ANO1 (0.43) | SCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912946-A1 | PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS | Eli Lilly and Company (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015767-A1 | PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |