Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24117771 | 0.86 | CTSK (0.40) | CTSKCA12CA1CA7CA14 | |
| SCHEMBL4818625 | 0.86 | CTSK (0.39) | CTSKCA14HDAC1HDAC2HDAC6 | |
| SCHEMBL4818294 | 0.86 | CTSK (0.39) | CTSKCA14HDAC1HDAC2HDAC6 | |
| SCHEMBL4818286 | 0.86 | CTSK (0.39) | CTSKCA14HDAC1HDAC2HDAC6 | |
| SCHEMBL3161490 | 0.85 | CA12 (0.39) | CTSKCA12CA1CA7CA14 | |
| SCHEMBL6327607 | 0.84 | GPR88 (0.36) | CTSKCA12CA1CA7CA14 | |
| SCHEMBL3161597 | 0.83 | CA14 (0.41) | CTSKCA12CA1CA7CA14 | |
| SCHEMBL4820504 | 0.82 | CTSK (0.41) | CTSKCA1CA7CA14HDAC1 | |
| SCHEMBL31572485 | 0.82 | EPHX2 (0.41) | CTSKCA12CA1CA7CA14 | |
| SCHEMBL14098625 | 0.82 | EPHX2 (0.41) | CTSKCA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924570-A1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | Argenta Discovery Limited (GB) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007017669-A1 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE | ARGENTA DISCOVERY LTD. (GB) | 2007-02-15 | — | — | WO | disclosed |