Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | MPO | P05164 | 7/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634057 | 0.95 | HTR2A (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632232 | 0.91 | HTR2A (0.65) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL1399398 | 0.91 | HTR2A (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL1399286 | 0.88 | MPO (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632194 | 0.88 | HTR2A (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4633963 | 0.86 | HTR2A (0.54) | HTR2ATRPM8KMT2AIDO1GPR84 | |
| SCHEMBL4633110 | 0.86 | HTR2A (0.54) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632198 | 0.86 | HTR2A (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL3190980 | 0.84 | HTR2A (0.51) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632661 | 0.84 | HTR2A (0.52) | HTR2AMPOTRPM8HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701940-B1 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI | LUNDBECK & CO AS H (DK) | 2008-05-28 | — | — | EP | claimed |