Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.65 |
| ▸ | MPO | P05164 | 9/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633110 | 0.91 | HTR2A (0.54) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632733 | 0.91 | HTR2A (0.54) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632198 | 0.91 | HTR2A (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4634057 | 0.91 | HTR2A (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4633098 | 0.91 | HTR2A (0.58) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL735716 | 0.90 | HTR2A (0.62) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632661 | 0.89 | HTR2A (0.52) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL1399411 | 0.89 | MPO (0.65) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632750 | 0.88 | HTR2A (0.60) | HTR2AMPOTRPM8HTR1AKMT2A | |
| SCHEMBL4632929 | 0.85 | IDO1 (0.55) | HTR2AMPOTRPM8HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701940-B1 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI | LUNDBECK & CO AS H (DK) | 2008-05-28 | — | — | EP | claimed |