SCHEMBL463283

SCHEMBL463283

Nc1cc2cccc(O)c2nc1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.55
NCF1 P14598 1/20 0.55
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
KDM4E B2RXH2 8/20 0.46
METAP2 P50579 2/20 0.46
PIM1 P11309 1/20 0.44
CYP1A2 P05177 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
ALOX12 P18054 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MMP2 P08253 1/20 0.44
CHRM1 P11229 1/20 0.44
TSHR P16473 1/20 0.44
COMT P21964 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9701465 0.81 METAP2 (0.52) PLAUNCF1KMT2AMEN1KDM4E
SCHEMBL28153007 0.81 KMT2A (0.60) PLAUNCF1KMT2AMEN1KDM4E
SCHEMBL3245077 0.80 PLAU (0.55) PLAUNCF1KMT2AMEN1KDM4E
Hydrochloric Acid SCHEMBL28213132 0.79 KMT2A (0.58) PLAUNCF1KMT2AMEN1KDM4E
SCHEMBL3246323 0.78 METAP2 (0.56) PLAUNCF1KMT2AMEN1KDM4E
SCHEMBL15845269 0.77 KMT2A (0.55) PLAUNCF1KMT2AMEN1KDM4E
SCHEMBL15845272 0.77 KMT2A (0.47) PLAUNCF1KMT2AMEN1KDM4E
SCHEMBL29363063 0.77 PLAU (0.47) PLAUNCF1KMT2AMEN1KDM4E
SCHEMBL4870295 0.76 MAPT (0.44) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL28203737 0.75 PLAU (0.46) PLAUNCF1KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2044146-B1 SCORCH SAFE FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2017-05-10 EP claimed
US-20160115294-A1 CURATIVE COMPOSITIONS, FLUOROPOLYMER COMPOSITIONS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2016-04-28 US claimed
WO-2014201140-A1 CURATIVE COMPOSITIONS, FLUOROPOLYMER COMPOSITIONS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-18 WO claimed
US-8906821-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-09 US claimed
EP-2445939-A2 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M Innovative Properties Company (US) 2012-05-02 EP claimed
US-20120065321-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2012-03-15 US claimed
WO-2010151610-A2 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-12-29 WO claimed
US-7666949-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-02-23 US claimed
EP-1397420-B1 FLUOROPOLYMER CURING SYSTEM 3M INNOVATIVE PROPERTIES CO (US) 2009-09-23 EP claimed
EP-2044146-A1 SCORCH SAFE FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2009-04-08 EP claimed
US-20020177666-A1 Fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-11-28 US claimed
WO-2002088228-A1 FLUOROPOLYMER CURING SYSTEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-11-07 WO claimed
WO-2002083755-A1 FLUOROPOLYMERS HAVING PENDANT IMIDATE STRUCTURES 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-24 WO claimed
WO-2002083756-A1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-24 WO claimed
US-20020145228-A1 Fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-10-10 US claimed
WO-2002060969-A1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-08-08 WO claimed
US-20020061977-A1 Imidate-containing fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-05-23 US claimed
US-20020055593-A1 Metal amine complex containing fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-05-09 US claimed
WO-2002024766-A2 IMIDATE-CONTAINING FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-03-28 WO claimed
WO-2002024772-A2 METAL AMINE COMPLEX CONTAINING FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-03-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065321-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS POLQ, QPCTL, NQO2 PLAU 2455/4885NCF1 3079/4885KMT2A 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.