Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633027 | 0.87 | KDM4E (0.56) | KMT2AMEN1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL4920511 | 0.84 | PIK3CG (0.71) | KMT2APIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL4633097 | 0.79 | MEN1 (0.49) | KMT2AMEN1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL6712892 | 0.77 | MEN1 (0.71) | KMT2AMEN1KCNH2POLBCACNA1F | |
| SCHEMBL4632214 | 0.76 | KDM4E (0.65) | KMT2AMEN1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL4633160 | 0.75 | PIK3CG (0.69) | KMT2AMEN1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL4633000 | 0.75 | PIK3CG (0.68) | KMT2APIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL10679862 | 0.75 | MEN1 (0.74) | KMT2AMEN1KCNH2POLBCACNA1F | |
| SCHEMBL9757365 | 0.75 | CACNA1F (0.61) | KMT2AMEN1KCNH2POLBCACNA1F | |
| SCHEMBL10683491 | 0.72 | MEN1 (0.67) | KMT2AMEN1KCNH2POLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139574-A1 | Novel quinoline derivatives | CADILA HEALTHCARE LIMITED | 2008-06-12 | — | — | US | claimed |
| EP-1927589-A1 | Quinoline derivatives | CADILA HEALTHCARE LTD. (IN) | 2008-06-04 | — | — | EP | claimed |
| US-20080139574-A1 | Novel quinoline derivatives | CADILA HEALTHCARE LIMITED | 2008-06-12 | — | — | US | disclosed |
| EP-1927589-A1 | Quinoline derivatives | CADILA HEALTHCARE LTD. (IN) | 2008-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139574-A1 | Novel quinoline derivatives | UGT1A7, CYP3A5, CYP3A7 | KMT2A 2849/4885MEN1 680/4885PIK3CG 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.