Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.71 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633000 | 0.91 | PIK3CG (0.68) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL4633160 | 0.88 | PIK3CG (0.69) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL4633027 | 0.87 | KDM4E (0.56) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL4633103 | 0.84 | KMT2A (0.51) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL4632270 | 0.83 | PIK3CG (0.72) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL4717454 | 0.82 | ALDH1A1 (0.73) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL10919718 | 0.81 | KDM4E (0.80) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL4632188 | 0.80 | PIK3CG (0.63) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL10809240 | 0.79 | KDM4E (1.00) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E | |
| SCHEMBL29350842 | 0.79 | KDM4E (1.00) | PIK3CGPIK3CDPIK3R1PIK3CAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139574-A1 | Novel quinoline derivatives | CADILA HEALTHCARE LIMITED | 2008-06-12 | — | — | US | claimed |
| US-20080139574-A1 | Novel quinoline derivatives | CADILA HEALTHCARE LIMITED | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139574-A1 | Novel quinoline derivatives | UGT1A7, CYP3A5, CYP3A7 | PIK3CG 3091/4885PIK3CD 1934/4885PIK3R1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.