Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | IL2 | P60568 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633505 | 0.91 | KMT2A (0.49) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL4634559 | 0.88 | KMT2A (0.49) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL4634518 | 0.81 | KMT2A (0.52) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL3615049 | 0.81 | KMT2A (0.57) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL4634602 | 0.78 | KMT2A (0.46) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL3604192 | 0.78 | KMT2A (0.57) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL26802311 | 0.78 | DYRK1A (0.43) | KMT2AKDM4ETSHRHPGDALDH1A1 | |
| SCHEMBL4633520 | 0.76 | KMT2A (0.53) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL3620308 | 0.76 | PRSS12 (0.51) | KMT2AMEN1KDM4ETSHRNPC1 | |
| SCHEMBL26805732 | 0.76 | HTT (0.48) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |