Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634559 | 0.90 | KMT2A (0.49) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL4633505 | 0.88 | KMT2A (0.49) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL4633611 | 0.81 | KMT2A (0.48) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL3618151 | 0.81 | KDM4C (0.58) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL4633165 | 0.78 | KMT2A (0.49) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL3620308 | 0.78 | PRSS12 (0.51) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL3604192 | 0.78 | KMT2A (0.57) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL4633579 | 0.75 | NPC1 (0.55) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL3615049 | 0.75 | KMT2A (0.57) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL4633171 | 0.73 | KMT2A (0.46) | KMT2ANPC1RAB9AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |