Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633168 | 1.00 | HNF4A (0.46) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL10584659 | 0.86 | IAPP (0.41) | ALDH1A1IAPPESR2ALOX5 | |
| SCHEMBL10584658 | 0.86 | IAPP (0.41) | ALDH1A1IAPPESR2ALOX5 | |
| SCHEMBL6446688 | 0.82 | GRIN2D (0.43) | ALDH1A1HPGDBCL2L1HSD17B10BACE1 | |
| SCHEMBL1588210 | 0.82 | GRIN2D (0.43) | ALDH1A1HPGDBCL2L1HSD17B10BACE1 | |
| SCHEMBL9496694 | 0.82 | GRIN2D (0.43) | ALDH1A1HPGDBCL2L1HSD17B10BACE1 | |
| SCHEMBL8894545 | 0.80 | IAPP (0.45) | ALDH1A1HPGDHSD17B10IAPPESR2 | |
| SCHEMBL2047855 | 0.80 | IAPP (0.45) | ALDH1A1HPGDHSD17B10IAPPESR2 | |
| SCHEMBL2047852 | 0.80 | IAPP (0.45) | ALDH1A1HPGDHSD17B10IAPPESR2 | |
| SCHEMBL6548196 | 0.79 | PDCD1 (0.47) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654266-B1 | NOVEL METATHESIS CATALYSTS | BOEHRINGER INGELHEIM INT (DE) | 2008-06-04 | — | — | EP | disclosed |
| US-7241898-B2 | Metathesis catalysts | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| EP-1654266-A1 | NOVEL METATHESIS CATALYSTS | Boehringer Ingelheim International GmbH (DE) | 2006-05-10 | — | — | EP | disclosed |
| US-20050049417-A1 | Metathesis catalysts | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-03-03 | — | — | US | disclosed |
| WO-2005016944-A1 | NOVEL METATHESIS CATALYSTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049417-A1 | Metathesis catalysts | CYP1B1, MSMO1, CYP1A1 | HNF4A 2268/4885HDAC4 4106/4885HDAC2 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.