Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2047855 | 1.00 | IAPP (0.45) | IAPPRELAERN1ESR1ESR2 | |
| SCHEMBL2047852 | 1.00 | IAPP (0.45) | IAPPRELAERN1ESR1ESR2 | |
| SCHEMBL12222499 | 0.89 | ERN1 (0.57) | IAPPERN1ESR1ESR2ALDH1A1 | |
| SCHEMBL9251021 | 0.88 | IAPP (0.60) | IAPPRELAERN1GAARAB9A | |
| SCHEMBL10584659 | 0.88 | IAPP (0.41) | IAPPRELAERN1ESR1ESR2 | |
| SCHEMBL9745412 | 0.88 | IAPP (0.60) | IAPPRELAERN1GAARAB9A | |
| SCHEMBL9251009 | 0.88 | IAPP (0.60) | IAPPRELAERN1GAARAB9A | |
| SCHEMBL10584658 | 0.88 | IAPP (0.41) | IAPPRELAERN1ESR1ESR2 | |
| SCHEMBL2158538 | 0.86 | ALDH1A1 (0.54) | IAPPESR1ESR2GAARAB9A | |
| SCHEMBL2158535 | 0.86 | ALDH1A1 (0.54) | IAPPESR1ESR2GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962181-A | OXIDATION, POLYMERIZATION, MANGANESE COMPLEX | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-06-08 | — | — | US | claimed |
| US-9637563-B2 | Surfactant composition | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2017-05-02 | — | — | US | disclosed |
| US-20160137755-A1 | SURFACTANT COMPOSITION | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-5691367-A | ANTIINFLAMMATORY AGENTS OR ANTIARTHRITIC AGENTS | ELI LILLY AND COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| EP-0391644-B1 | Aryl-substituted rhodanine derivatives | LILLY CO ELI (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5356917-A | Antiischemic, antiinflammatory, antiarthritic agents, treat-ment of dystrophic mammals | ELI LILLY AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| US-5158966-A | Aryl-substituted rhodanine derivatives | THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0500337-A1 | Composition containing aryl-substituted rhodanine derivatives for the treatment of type I diabetes | UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5023310-A | Chain extended epoxy resin | BASF AKTIENGESELLSCHAFT | 1991-06-11 | — | — | US | disclosed |
| EP-0391644-A2 | Aryl-substituted rhodanine derivatives | ELI LILLY AND COMPANY (US) | 1990-10-10 | — | — | EP | disclosed |
| US-4525572-A | TETRAARYL-SUBSTITUTED ETHANE WITH HYDROXY OR HALO GROUPS | CIBA-GEIGY CORPORATION (US) | 1985-06-25 | — | — | US | disclosed |
| US-4463147-A | MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| EP-0014816-B1 | POLYCYCLIC POLYPHENOLS WITH PROPENYL GROUPS AND CURABLE MIXTURES BASED ON MALEIMIDES AND PROPENYL-SUBSTITUTED PHENOLS | CIBA-GEIGY AG (CH) | 1983-08-24 | — | — | EP | disclosed |
| US-4384129-A | POLYMER MONOMERS | CIBA-GEIGY CORPORATION (US) | 1983-05-17 | — | — | US | disclosed |
| US-4371719-A | Curable mixtures based on maleimides and propenyl-substituted phenols, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1983-02-01 | — | — | US | disclosed |
| EP-0013258-B1 | PROPENYL-SUBSTITUTED PHENOLGLYCIDYL ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1982-07-07 | — | — | EP | disclosed |
| US-4288583-A | MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0014816-A1 | Polycyclic polyphenols with propenyl groups and curable mixtures based on maleimides and propenyl-substituted phenols | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |
| EP-0013258-A1 | Propenyl-substituted phenolglycidyl ethers, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1980-07-09 | — | — | EP | disclosed |
| US-3962181-A | OXIDATION, POLYMERIZATION, MANGANESE COMPLEX | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-06-08 | — | — | US | disclosed |