Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4633238

C=CCN(CC=C)CCC.N

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR1A P08908 2/20 0.31
ADRA2A P08913 2/20 0.31
ADRA2B P18089 2/20 0.31
ADRA2C P18825 2/20 0.31
HTR1D P28221 2/20 0.31
HTR2A P28223 2/20 0.31
HTR2C P28335 2/20 0.31
HTR1E P28566 2/20 0.31
SLC6A4 P31645 2/20 0.31
ADRA1A P35348 2/20 0.31
HRH1 P35367 2/20 0.31
ADRA1B P35368 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213816 0.97 TSHR (0.38) TSHRKMT2AMEN1ALDH1A1POLB
Bromide SCHEMBL28746663 0.94 TSHR (0.36) TSHRKMT2AMEN1ALDH1A1POLB
Hydrochloric Acid SCHEMBL7265724 0.94 TSHR (0.36) TSHRKMT2AMEN1ALDH1A1POLB
Iodide SCHEMBL27887900 0.94 TSHR (0.36) TSHRKMT2AMEN1ALDH1A1POLB
SCHEMBL435287 0.92 TSHR (0.38) TSHRKMT2AMEN1ALDH1A1POLB
Hydrochloric Acid SCHEMBL22771642 0.89 TSHR (0.36) TSHRKMT2AMEN1ALDH1A1POLB
Water SCHEMBL31456245 0.89 TSHR (0.36) TSHRKMT2AMEN1ALDH1A1POLB
SCHEMBL8644002 0.86
SCHEMBL10580889 0.86 TSHR (0.35) TSHRKMT2AMEN1ALDH1A1POLB
SCHEMBL21574010 0.84 TSHR (0.33) TSHRKMT2AMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475360-B1 USE OF AN ADDITIVE COMPOSITION FOR THE PREPARATION OF POLYCONDENSATION POLYMERS CLARIANT PLASTICS & COATINGS LTD (CH) 2024-05-22 EP disclosed
US-10920069-B2 Use of an additive composition for the preparation of polycondensation polymers CLARIANT PLASTICS & COATINGS LTD (CH) 2021-02-16 US disclosed
US-20190161609-A1 USE OF AN ADDITIVE COMPOSITION FOR THE PREPARATION OF POLYCONDENSATION POLYMERS CLARIANT PLASTICS & COATINGS LTD (CH) 2019-05-30 US disclosed
EP-3475360-A1 USE OF AN ADDITIVE COMPOSITION FOR THE PREPARATION OF POLYCONDENSATION POLYMERS Clariant Plastics & Coatings Ltd (CH) 2019-05-01 EP disclosed
WO-2018001704-A1 USE OF AN ADDITIVE COMPOSITION FOR THE PREPARATION OF POLYCONDENSATION POLYMERS CLARIANT INTERNATIONAL LTD (CH) 2018-01-04 WO disclosed
EP-3263639-A1 USE OF AN ADDITIVE COMPOSITION FOR THE PREPARATION OF POLYCONDENSATION POLYMERS Clariant International Ltd (CH) 2018-01-03 EP disclosed
US-9458373-B2 Composition and method for reducing hydrate agglomeration ECOLAB USA INC. (US) 2016-10-04 US disclosed
EP-2651877-B1 COMPOSITION AND METHOD FOR REDUCING HYDRATE AGGLOMERATION NALCO CO (US) 2016-03-09 EP disclosed
US-8618025-B2 Composition and method for reducing hydrate agglomeration NALCO COMPANY (US) 2013-12-31 US disclosed
US-20120157351-A1 COMPOSITION AND METHOD FOR REDUCING HYDRATE AGGLOMERATION APERGY ESP SYSTEMS, LLC 2012-06-21 US disclosed
EP-0800548-B2 POLYCAPROLACTAM PRODUCED USING A NOVEL METHOD OF CHAIN CONTROL INVENTA FISCHER AG (CH) 2008-03-05 EP disclosed
CN-1090645-C Polycaprolactam with novel chain regulation EMS INVESTA AG (CH) 2002-09-11 CN disclosed
EP-0800548-B1 POLYCAPROLACTAM PRODUCED USING A NOVEL METHOD OF CHAIN CONTROL INVENTA FISCHER AG (CH) 2002-04-03 EP disclosed
US-6069217-A THICKENER PRODUCED BY LINKING POLYURETHANE COMPRISING POLYISOCYANATE, POLYETHER POLYOL, MODIFYING AGENT AND CAPPING AGENT WITH ALKALI SWELLABLE COPOLYMER COMPRISING ETHYLENICALLY UNSATURATED CARBOXYLIC ACID AND NONIONIC VINYL MONOMERS RHEOX, INC. (US) 2000-05-30 US disclosed
US-5917004-A POLYMERIZATION CARRIED OUT IN PRESENCE OF 4-AMINO-2,2,6,6-TETRAALKYLPIPERIDINE AND CARBOXY OR AMINE-CONTAINING DIALKYL PHENOL EMS-INVENTA AG (CH) 1999-06-29 US disclosed
US-5807972-A USING AROMATIC DICARBOXYLIC ACID, DIAMINE AND 4-AMINO-2,2,6,6-TETRAALKYLPIPERIDINE EMS-INVENTA AG (CH) 1998-09-15 US disclosed
CN-1166846-A Polycaprolactam produced using a novel method of chain control INVENTA AG (CH) 1997-12-03 CN disclosed
US-4499233-A MODIFIED ENDCAPPED POLYETHYERURETHANE COPOLYMER NL INDUSTRIES, INC. (US) 1985-02-12 US disclosed
EP-0127950-A1 Preparation of water dispersible, modified polyurethanes RHEOX INTERNATIONAL, INC. (US) 1984-12-12 EP disclosed
US-4436862-A POLYETHERURETHANE COPOLYMERS NL INDUSTRIES, INC. (US) 1984-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157351-A1 COMPOSITION AND METHOD FOR REDUCING HYDRATE AGGLOMERATION H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AQP1, AQP3 TSHR 3665/4885KMT2A 2872/4885MEN1 2002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.