Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 9/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633570 | 0.90 | S1PR2 (0.51) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL4634096 | 0.90 | S1PR2 (0.51) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL4291153 | 0.88 | S1PR2 (0.51) | S1PR2S1PR1S1PR3LPAR2S1PR4 | |
| SCHEMBL4632564 | 0.85 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL4633302 | 0.85 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL4633251 | 0.85 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL4634024 | 0.82 | MEN1 (0.48) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL4633518 | 0.79 | S1PR5 (0.47) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4633616 | 0.79 | S1PR5 (0.47) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4298459 | 0.78 | S1PR2 (0.52) | S1PR2S1PR1S1PR3LPAR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650186-B1 | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-06-04 | — | — | EP | claimed |