Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 9/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633285 | 0.90 | S1PR2 (0.50) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4633570 | 0.89 | S1PR2 (0.51) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4293994 | 0.88 | S1PR2 (0.52) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4633302 | 0.84 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4633568 | 0.84 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4632564 | 0.84 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4633251 | 0.84 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4634024 | 0.81 | MEN1 (0.48) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL4634069 | 0.78 | KDM1A (0.38) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL4291153 | 0.78 | S1PR2 (0.51) | S1PR2S1PR1S1PR3LPAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650186-B1 | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-06-04 | — | — | EP | claimed |