Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633325 | 1.00 | GABRP (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1558822 | 0.74 | — | — | |
| SCHEMBL3592245 | 0.70 | RNPEP (0.30) | — | |
| SCHEMBL11788692 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL11789748 | 0.68 | GABRA1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7108981 | 0.63 | NISCH (0.39) | ALDH1A1 | |
| SCHEMBL5902247 | 0.63 | — | — | |
| SCHEMBL5902243 | 0.63 | — | — | |
| SCHEMBL8427654 | 0.60 | TAAR1 (0.44) | — | |
| SCHEMBL844981 | 0.59 | GABRP (0.31) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930335-A1 | Cephalosporines having cyclic aminoguanidine substituents as Antibiotics | Nabriva Therapeutics AG (AT) | 2008-06-11 | — | — | EP | disclosed |
| US-6440957-B1 | Cephalosporines having cyclic aminoguanidine substituents as antibiotics | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2002-08-27 | — | — | US | disclosed |
| EP-1082326-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999048896-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1999-09-30 | — | — | WO | disclosed |