⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633371 | 1.00 | — | — | |
| SCHEMBL4633372 | 1.00 | — | — | |
| SCHEMBL6603156 | 0.74 | — | — | |
| SCHEMBL829988 | 0.74 | CYP2D6 (0.40) | — | |
| SCHEMBL6602740 | 0.74 | — | — | |
| SCHEMBL873651 | 0.74 | — | — | |
| Lithium SCHEMBL29627538 | 0.73 | CAD (0.44) | — | |
| Hydrochloric Acid SCHEMBL28100978 | 0.73 | CAD (0.44) | — | |
| SCHEMBL11789358 | 0.73 | — | — | |
| Hydroxyamine SCHEMBL6694548 | 0.71 | CAD (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930335-A1 | Cephalosporines having cyclic aminoguanidine substituents as Antibiotics | Nabriva Therapeutics AG (AT) | 2008-06-11 | — | — | EP | disclosed |
| US-6440957-B1 | Cephalosporines having cyclic aminoguanidine substituents as antibiotics | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2002-08-27 | — | — | US | disclosed |
| EP-1082326-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999048896-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1999-09-30 | — | — | WO | disclosed |