Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CAD | P27708 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873651 | 0.81 | — | — | |
| SCHEMBL6603156 | 0.81 | — | — | |
| SCHEMBL6602740 | 0.81 | — | — | |
| Lithium SCHEMBL29627538 | 0.79 | CAD (0.44) | CYP2D6LMNABLMALOX15CYP1A2 | |
| Hydrochloric Acid SCHEMBL28100978 | 0.79 | CAD (0.44) | CYP2D6LMNABLMALOX15CYP1A2 | |
| Hydroxyamine SCHEMBL6694548 | 0.77 | CAD (0.43) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL4459100 | 0.77 | CAD (0.39) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL4633368 | 0.74 | — | — | |
| SCHEMBL4633371 | 0.74 | — | — | |
| SCHEMBL11789358 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516132-A1 | Anti-neuronotoxic activity and therapeutic applications of GM1 ganglioside methyl ester | FIDIA S.p.A. (IT) | 1992-12-02 | — | — | EP | claimed |
| EP-2248902-B1 | Precise breeding | SIMPLOT CO J R (US) | 2016-08-10 | — | — | EP | disclosed |
| US-RE45722-E1 | Precise breeding | J.R. SIMPLOT COMPANY (US) | 2015-10-06 | — | — | US | disclosed |
| CN-102978236-B | Precise breeding | SIMPLOT CO. J. R. (US) | 2015-09-09 | — | — | CN | disclosed |
| US-20140080140-A1 | SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS | THE INSTITUTE FOR ETHNOMEDICINE | 2014-03-20 | — | — | US | disclosed |
| US-8674177-B2 | Precise breeding | J.R. SIMPLOT COMPANY (US) | 2014-03-18 | — | — | US | disclosed |
| US-20130254938-A1 | PRECISE BREEDING-SIMULTANEOUS SILENCING | J.R. SIMPLOT COMPANY | 2013-09-26 | — | — | US | disclosed |
| US-8541184-B2 | Screening for neurotoxic amino acid associated with neurological disorders | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2013-09-24 | — | — | US | disclosed |
| US-8502027-B2 | Precise breeding—low acrylamide foods | J.R. SIMPLOT COMPANY (US) | 2013-08-06 | — | — | US | disclosed |
| US-20130074222-A1 | PRECISE BREEDING | J.R. SIMPLOT COMPANY | 2013-03-21 | — | — | US | disclosed |
| EP-0661973-A4 | METHOD OF PREVENTING NMDA RECEPTOR COMPLEX-MEDIATED NEURONAL DAMAGE. | CHILDRENS MEDICAL CENTER (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5801203-A | Nitroglycerine patch | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1998-09-01 | — | — | US | disclosed |
| US-5747545-A | SCREENING COMPOUNDS BY DETERMINING CHANNEL BLOCKING TIME | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1998-05-05 | — | — | US | disclosed |
| US-5438130-A | Fucosylated guanosine disulfates as excitatory amino acid antagonists | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0661973-A1 | METHOD OF PREVENTING NMDA RECEPTOR COMPLEX-MEDIATED NEURONAL DAMAGE | The Children's Medical Center Corporation (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994006428-A1 | METHOD OF PREVENTING NMDA RECEPTOR COMPLEX-MEDIATED NEURONAL DAMAGE | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1994-03-31 | — | — | WO | disclosed |
| EP-0341895-B1 | AMINO ACIDS IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | AJINOMOTO CO., INC. (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0516132-A1 | Anti-neuronotoxic activity and therapeutic applications of GM1 ganglioside methyl ester | FIDIA S.p.A. (IT) | 1992-12-02 | — | — | EP | disclosed |
| US-5028622-A | Administration of amino acids as treatment for neurodegenerative disorders | AJINOMOTO COMPANY, INC. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0341895-A1 | Amino acids in the treatment of neurodegenerative disorders | AJINOMOTO CO., INC. (JP) | 1989-11-15 | — | — | EP | disclosed |