SCHEMBL4633499

SCHEMBL4633499

CCCOC(=O)C(=COC(=O)CC(C)=O)OC(=O)CC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
HCAR2 Q8TDS4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13276060 0.85 GAA (0.38) GAAMGAMSIMGAM2HCAR2
SCHEMBL13276062 0.85 GAA (0.38) GAAMGAMSIMGAM2HCAR2
SCHEMBL2208079 0.82 GAA (0.38) GAAMGAMSIMGAM2HCAR2
SCHEMBL6292361 0.73 TSHR (0.41) GAAMGAMSIMGAM2HCAR2
SCHEMBL5832311 0.73 ALDH1A1 (0.44) GAAMGAMSIMGAM2HCAR2
SCHEMBL13275367 0.71 GLO1 (0.41) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL13275368 0.71 GLO1 (0.41) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL243835 0.71 MGAM (0.52) GAAMGAMSIMGAM2HCAR2
SCHEMBL6449776 0.70 MGAM (0.46) GAAMGAMSIMGAM2
SCHEMBL15281956 0.69 MGAM (0.50) GAAMGAMSIMGAM2HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717280-B1 Compatibilization of esters with latices ROHM & HAAS (US) 2008-06-11 EP disclosed
US-7288509-B2 Compatibilization of esters with latices ROHM AND HAAS COMPANY (US) 2007-10-30 US disclosed
EP-1717280-A1 Compatibilization of esters with latices Rohm and Haas Company (US) 2006-11-02 EP disclosed
US-20060241009-A1 Compatibilization of esters with latices KOHR ALAN W 2006-10-26 US disclosed
EP-0943668-B1 Process of improving the leveling of a floor polish composition ROHM & HAAS (US) 2005-02-09 EP disclosed
EP-0943668-A1 Process of improving the leveling of a floor polish composition ROHM AND HAAS COMPANY (US) 1999-09-22 EP disclosed