Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP5 | Q96HI0 | 13/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 13/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 13/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604734 | 0.91 | SENP5 (0.50) | SENP5SENP2SENP1LRRK2LMNA | |
| SCHEMBL4634455 | 0.89 | MAPT (0.50) | SENP5SENP2SENP1LRRK2LMNA | |
| SCHEMBL4604241 | 0.85 | SENP2 (0.46) | SENP5SENP2SENP1LRRK2LMNA | |
| SCHEMBL4634441 | 0.84 | LRRK2 (0.41) | SENP5SENP2SENP1LRRK2LMNA | |
| SCHEMBL4603197 | 0.81 | SENP5 (0.48) | SENP5SENP2SENP1LMNAMAPT | |
| SCHEMBL4632927 | 0.80 | SENP2 (0.59) | SENP5SENP2SENP1LMNAMAPT | |
| SCHEMBL4634951 | 0.79 | KDM4E (0.67) | SENP5SENP2SENP1KDM4EALDH1A1 | |
| SCHEMBL4634468 | 0.78 | PTPN2 (0.56) | SENP5SENP2SENP1LMNAMAPT | |
| SCHEMBL4634967 | 0.77 | EDNRA (0.54) | SENP5SENP2SENP1KDM4EALDH1A1 | |
| SCHEMBL4633954 | 0.76 | MAPT (0.55) | SENP5SENP2SENP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |