Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623718 | 0.78 | NPC1 (0.37) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL3616443 | 0.77 | KMT2A (0.36) | MAPTALDH1A1TSHRGAAHPGD | |
| SCHEMBL3618059 | 0.72 | PRSS12 (0.40) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL3617006 | 0.72 | PRSS12 (0.37) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL3621092 | 0.72 | PRSS12 (0.39) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL3614431 | 0.72 | PRSS12 (0.39) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL3611094 | 0.71 | NPC1 (0.35) | DGAT1MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3622782 | 0.70 | PRSS12 (0.38) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL3617278 | 0.70 | KDM4E (0.48) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL3619119 | 0.70 | PRSS12 (0.39) | MAPTALDH1A1HTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |