Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621092 | 0.94 | PRSS12 (0.39) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3618059 | 0.90 | PRSS12 (0.40) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3608503 | 0.88 | PRSS12 (0.43) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3622782 | 0.88 | PRSS12 (0.38) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3619119 | 0.88 | PRSS12 (0.39) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3609334 | 0.87 | PRSS12 (0.38) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3621698 | 0.87 | PRSS12 (0.38) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3621078 | 0.87 | NAMPT (0.42) | KDM4EMEN1KMT2AF10NPC1 | |
| SCHEMBL3621920 | 0.86 | F10 (0.43) | PRSS12KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3622492 | 0.86 | F10 (0.40) | PRSS12KDM4EMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | BAYER HEALTHCARE AG (DE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | PPOX, XDH, PNPO | PRSS12 3975/4885KDM4E 3828/4885MEN1 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.