Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SENP5 | Q96HI0 | 2/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635045 | 0.91 | PTPN1 (0.63) | PTPN2PTPN1KMT2AALDH1A1NOD2 | |
| SCHEMBL4603919 | 0.90 | MAOB (0.57) | PTPN2PTPN1KMT2AALDH1A1NOD2 | |
| SCHEMBL4632954 | 0.89 | PTPN1 (0.57) | PTPN2PTPN1KMT2AALDH1A1NOD2 | |
| SCHEMBL4634468 | 0.88 | PTPN2 (0.56) | PTPN2PTPN1KMT2AALDH1A1NOD2 | |
| SCHEMBL4635101 | 0.88 | PTPN2 (0.56) | PTPN2PTPN1KMT2AALDH1A1MEN1 | |
| SCHEMBL4634448 | 0.87 | KMT2A (0.73) | KMT2AALDH1A1NOD2MEN1MAPT | |
| SCHEMBL4634967 | 0.83 | EDNRA (0.54) | PTPN2PTPN1ALDH1A1MAOBSENP5 | |
| SCHEMBL4634440 | 0.83 | SENP5 (0.52) | PTPN2PTPN1KMT2AALDH1A1MAPT | |
| SCHEMBL4603478 | 0.82 | MAOB (0.51) | PTPN2PTPN1KMT2AALDH1A1NOD2 | |
| SCHEMBL4632950 | 0.82 | SENP5 (0.60) | PTPN2PTPN1KMT2AALDH1A1NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |