Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PRSS12 | P56730 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635045 | 0.91 | PTPN1 (0.63) | PTPN2PTPN1MCL1SENP5SENP2 | |
| SCHEMBL4603123 | 0.90 | GABRA1 (0.56) | PTPN2PTPN1MCL1SENP5SENP2 | |
| SCHEMBL4632954 | 0.89 | PTPN1 (0.57) | PTPN2PTPN1MCL1SENP5SENP2 | |
| SCHEMBL4633595 | 0.88 | PTPN2 (0.56) | PTPN2PTPN1MCL1SENP5SENP2 | |
| SCHEMBL4634468 | 0.88 | PTPN2 (0.56) | PTPN2PTPN1MCL1SENP5SENP2 | |
| SCHEMBL4634481 | 0.85 | ALDH1A1 (0.60) | SENP5SENP2SENP1GABRA1GABRA5 | |
| SCHEMBL4634967 | 0.83 | EDNRA (0.54) | PTPN2PTPN1SENP5SENP2SENP1 | |
| SCHEMBL4634440 | 0.83 | SENP5 (0.52) | PTPN2PTPN1MCL1SENP5SENP2 | |
| SCHEMBL4602915 | 0.82 | GABRA1 (0.50) | PTPN2PTPN1SENP5SENP2SENP1 | |
| SCHEMBL4603300 | 0.82 | PTPN2 (0.51) | PTPN2PTPN1MCL1SENP5SENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |