Butyl Isothiocyanate

Butyl Isothiocyanate

SCHEMBL4633771

CCCC(C)O.CCCCN=C=S

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.55
MIF P14174 5/20 0.41
TRPA1 O75762 10/20 0.39
KEAP1 Q14145 2/20 0.36
NFE2L2 Q16236 2/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
BACH1 O14867 1/20 0.36
MAFK O60675 1/20 0.36
EGFR P00533 1/20 0.36
PTGS2 P35354 1/20 0.36
GSK3B P49841 1/20 0.35
TRPV1 Q8NER1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL364007 0.82 MIF (0.50) NAAAMIFTRPA1KEAP1NFE2L2
Butyl Isothiocyanate SCHEMBL152568 0.81
SCHEMBL25335000 0.79
Butyl Isothiocyanate SCHEMBL27915601 0.79
Butyl Isothiocyanate SCHEMBL18154858 0.76 NAAA (0.59) NAAAMIFTRPA1KEAP1NFE2L2
SCHEMBL25332777 0.76 NAAA (0.48) NAAAMIFTRPA1KEAP1NFE2L2
Butyl Isothiocyanate SCHEMBL28049419 0.74 NAAA (0.70) NAAAMIFTRPA1KEAP1NFE2L2
1-Isothiocyanatopentane SCHEMBL175645 0.74
SCHEMBL1457042 0.72 NAAA (1.00) NAAAMIFTRPA1KEAP1NFE2L2
SCHEMBL9831163 0.72 NAAA (1.00) NAAAMIFTRPA1KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928992-A1 CONSUMER PRODUCTS HAVING VARYING ODORS Henkel AG & Co. KGaA (DE) 2008-06-11 EP disclosed
WO-2007028479-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed