⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4103971 | 0.79 | — | — | |
| SCHEMBL3092709 | 0.74 | HRH4 (0.31) | — | |
| SCHEMBL4957048 | 0.72 | PAOX (0.30) | — | |
| SCHEMBL14152524 | 0.71 | ALOX5 (0.39) | — | |
| SCHEMBL14311842 | 0.70 | HSD17B10 (0.39) | — | |
| SCHEMBL14889676 | 0.69 | ALOX5 (0.43) | — | |
| SCHEMBL203010 | 0.69 | — | — | |
| SCHEMBL6685524 | 0.68 | — | — | |
| SCHEMBL4956527 | 0.67 | ALOX5 (0.44) | — | |
| SCHEMBL14615688 | 0.63 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | claimed |
| US-20060013784-A1 | Novel dimercaptoamides, compositions comprising them as reducing agents, and processes for permanently reshaping keratin fibers therewith | L'OREAL S.A. (FR) | 2006-01-19 | — | — | US | claimed |
| EP-1584615-A1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | L'OREAL (FR) | 2005-10-12 | — | — | EP | claimed |
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | disclosed |
| US-20060013784-A1 | Novel dimercaptoamides, compositions comprising them as reducing agents, and processes for permanently reshaping keratin fibers therewith | L'OREAL S.A. (FR) | 2006-01-19 | — | — | US | disclosed |
| EP-1584615-A1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | L'OREAL (FR) | 2005-10-12 | — | — | EP | disclosed |
| US-6258851-B1 | ENZYME INHIBITORS OF PROTEASES OR METALLOENZYMES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-07-10 | — | — | US | disclosed |
| EP-0971887-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998046563-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-10-22 | — | — | WO | disclosed |