SCHEMBL4633934

SCHEMBL4633934

O=c1c2ccccc2sc2cccc([S+]([O-])c3cccc4sc5ccccc5c(=O)c34)c12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
ALDH1A1 P00352 5/20 0.43
POLB P06746 4/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
GAA P10253 1/20 0.43
KDM4E B2RXH2 2/20 0.42
GPR3 P46089 1/20 0.42
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
BLM P54132 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576668 0.86 GPR3 (0.48) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL27688939 0.83 MAPT (0.45) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL4634508 0.78 KDM4E (0.49) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL30996499 0.76 MAPT (0.44) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL116182 0.74 MAOA (0.68) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL9128466 0.74 MAPT (0.50) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL151907 0.74 KDM4E (0.54) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL425780 0.74 MAPT (0.58) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL1871982 0.74 MAPT (0.50) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL31379948 0.74 MAPT (0.58) MAPTNPC1RAB9ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58120605-A None JP disclosed
JP-10212286-A None JP disclosed
JP-10182634-A None JP disclosed
CN-111138411-B Ultraviolet light promoted synthesis method of thioxanthone compound 浙江工业大学 2021-06-15 CN disclosed
CN-111138411-A Ultraviolet light promoted synthesis method of thioxanthone compound 浙江工业大学 2020-05-12 CN disclosed
CN-101090897-B Novel fused ring compounds, and use thereof as cationic photoinitiators SUN CHEMICAL CORP 2013-03-27 CN disclosed
CN-100439358-C Thioxanthone derivatives and their use as cationic photoinitiators TAYO CHEMICAL CO (US) 2008-12-03 CN disclosed
EP-1480967-B8 FUSED RING COMPOUNDS, AND THEIR USE AS CATIONIC PHOTOINITIATORS SUN CHEMICAL CORP (US) 2008-10-01 EP disclosed
EP-1480967-B1 FUSED RING COMPOUNDS, AND THEIR USE AS CATIONIC PHOTOINITIATORS SUN CHEMICAL CORP (US) 2008-06-04 EP disclosed
US-7335782-B2 Thioxanthone derivatives, and their use as cationic photoinitiators SUN CHEMICAL CO. (US) 2008-02-26 US disclosed
US-20050165126-A1 Thioxanthone derivatives, and their use as cationic photoinitiators SUN CHEMICAL CORPORATION 2005-07-28 US disclosed
EP-1480967-A1 NOVEL FUSED RING COMPOUNDS, AND THEIR USE AS CATIONIC PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2004-12-01 EP disclosed
EP-1480968-A1 THIOXANTHONE DERIVATIVES, AND THEIR USE AS CATIONIC PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2004-12-01 EP disclosed
WO-2003072567-A1 NOVEL FUSED RING COMPOUNDS, AND THEIR USE AS CATIONIC PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2003-09-04 WO disclosed
WO-2003072568-A1 THIOXANTHONE DERIVATIVES, AND THEIR USE AS CATIONIC PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2003-09-04 WO disclosed
JP-H10212286-A PHOTOINITIATOR, ENERGY RAY-HARDENABLE COMPOSITION CONTAINING THE SAME AND HARDENED MATERIAL THEREOF NIPPON KAYAKU CO LTD 1998-08-11 JP disclosed
JP-H10182634-A PHOTOPOLYMERIZATION INITIATOR, ENERGY RAY-CURABLE COMPOSITION AND CURED PRODUCT NIPPON KAYAKU CO LTD 1998-07-07 JP disclosed
US-5432049-A Photosensitive, indicators, filters CIBA-GEIGY CORPORATION (US) 1995-07-11 US disclosed
US-5310909-A Photosensitizers and color indicators or color filters CIBA-GEIGY CORPORATION (US) 1994-05-10 US disclosed
JP-S58120605-A CURING OF PHOTOPOLYMERIZABLE RESIN COMPOSITION USING THIOXANTHONE SULFOXIDE OR THIOXANTHONE SULFODIOXIDE DERIVATIVE NIPPON KAYAKU CO LTD 1983-07-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050165126-A1 Thioxanthone derivatives, and their use as cationic photoinitiators TH, TET1, KDM7A MAPT 1743/4885NPC1 4258/4885RAB9A 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.