Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635043 | 0.89 | CXCR2 (0.55) | CXCR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4632905 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMAPTNOD2 | |
| SCHEMBL4633878 | 0.87 | CXCR2 (0.46) | CXCR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4633540 | 0.86 | CXCR2 (0.51) | CXCR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4633874 | 0.85 | ALDH1A1 (0.56) | CXCR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4635016 | 0.81 | CXCR2 (0.43) | CXCR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4632951 | 0.81 | FFAR1 (0.45) | ALDH1A1KMT2ALMNAMAPTNOD2 | |
| SCHEMBL4633609 | 0.80 | LMNA (0.54) | CXCR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4633576 | 0.79 | KMT2A (0.50) | CXCR2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4634428 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMAPTNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |