Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436867 | 0.84 | NPC1 (0.60) | NPC1RAB9ALMNATRPM8 | |
| SCHEMBL1205605 | 0.82 | LMNA (0.75) | LMNAL3MBTL1FFAR1FFAR4 | |
| SCHEMBL8849741 | 0.81 | FFAR1 (0.67) | LMNAL3MBTL1FFAR1FFAR4 | |
| SCHEMBL8551105 | 0.81 | LMNA (0.63) | LMNAL3MBTL1FFAR1FFAR4 | |
| SCHEMBL3693042 | 0.80 | LMNA (0.62) | LMNAL3MBTL1FFAR1FFAR4 | |
| SCHEMBL5283269 | 0.79 | FFAR1 (0.56) | LMNAL3MBTL1FFAR1TRPM8FFAR4 | |
| SCHEMBL10013763 | 0.79 | NPC1 (0.81) | NPC1RAB9ALMNATRPM8 | |
| SCHEMBL469923 | 0.78 | FFAR1 (0.69) | LMNAL3MBTL1FFAR1FFAR4 | |
| SCHEMBL24723566 | 0.77 | LMNA (0.62) | LMNAL3MBTL1FFAR1FFAR4 | |
| SCHEMBL1586881 | 0.77 | FFAR1 (0.63) | LMNAL3MBTL1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |