SCHEMBL4634007

SCHEMBL4634007

CCN1c2ccccc2Sc2cc(C=O)cc(N(N)c3ccccc3)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.38
▸ MEN1 O00255 6/20 0.38
▸ KMT2A Q03164 6/20 0.38
▸ USP2 O75604 1/20 0.38
▸ IDE P14735 1/20 0.38
▸ CRHBP P24387 1/20 0.38
▸ CRHR2 Q13324 1/20 0.38
▸ ALDH1A1 P00352 7/20 0.38
▸ HPGD P15428 3/20 0.38
▸ HTT P42858 2/20 0.38
▸ POLB P06746 1/20 0.37
▸ NPC1 O15118 3/20 0.35
▸ RAB9A P51151 3/20 0.35
▸ MAPK1 P28482 3/20 0.35
▸ THRB P10828 1/20 0.35
▸ KDM1A O60341 4/20 0.35
▸ PTGS1 P23219 2/20 0.35
▸ PTGS2 P35354 1/20 0.35
▸ CYP2D6 P10635 4/20 0.35
▸ ALOX15 P16050 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787347 0.83 ALDH1A1 (0.40) MAPTMEN1KMT2AUSP2IDE
SCHEMBL31481617 0.73 ALDH1A1 (0.48) MAPTMEN1KMT2AUSP2IDE
SCHEMBL4632567 0.73 ALDH1A1 (0.48) MAPTMEN1KMT2AUSP2IDE
SCHEMBL28362169 0.68 ALDH1A1 (0.48) MAPTMEN1KMT2AUSP2IDE
SCHEMBL29376040 0.66 PDF (0.48) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL25842328 0.66 PDF (0.48) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL29557425 0.66 KDM1A (0.61) MAPTKMT2AALDH1A1HPGDHTT
SCHEMBL293951 0.66 KDM1A (0.61) MAPTKMT2AALDH1A1HPGDHTT
SCHEMBL8185277 0.66 ALDH1A1 (0.39) MAPTMEN1KMT2AUSP2IDE
SCHEMBL29773802 0.66 ALDH1A1 (0.39) MAPTMEN1KMT2AUSP2IDE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1530093-B1 Organophotoreceptor with charge transport material with a hydrazone group linked to a heterocyclic group SAMSUNG ELECTRONICS CO LTD (KR) 2008-06-04 — — EP disclosed
US-7169520-B2 Organophotoreceptor with charge transport material with a hydrazone group linked to a heterocyclic group SAMSUNG ELECTRONICS CO., LTD (KR) 2007-01-30 — — US disclosed
EP-1530095-B1 Organophotoreceptor with charge transport material having a hydrazone group linked to an epoxy group and a heterocyclic ring SAMSUNG ELECTRONICS CO LTD (KR) 2007-01-03 — — EP disclosed
US-7083884-B2 Organophotoreceptor with charge transport material having a hydrazone group linked to an epoxy group and a heterocyclic ring SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-08-01 — — US disclosed
EP-1530093-A2 Organophotoreceptor with charge transport material with a hydrazone group linked to a heterocyclic group Samsung Electronics Co., Ltd. (KR) 2005-05-11 — — EP disclosed
EP-1530095-A2 Organophotoreceptor with charge transport material having a hydrazone group linked to an epoxy group and a heterocyclic ring Samsung Electronics Co., Ltd. (KR) 2005-05-11 — — EP disclosed
US-20050095519-A1 Organophotoreceptor with charge transport material with a hydrazone group linked to a heterocyclic group S-PRINTING SOLUTION CO., LTD. (KR) 2005-05-05 — — US disclosed
US-20050089781-A1 Organophotoreceptor with charge transport material having a hydrazone group linked to an epoxy group and a heterocyclic ring S-PRINTING SOLUTION CO., LTD. (KR) 2005-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050095519-A1 Organophotoreceptor with charge transport material with a hydrazone group linked to a heterocyclic group NR2E3, NR4A3, CHRM3 MAPT 3136/4885MEN1 2664/4885KMT2A 3581/4885
US-20050089781-A1 Organophotoreceptor with charge transport material having a hydrazone group linked to an epoxy group and a heterocyclic ring NR2E3, NR4A3, CHRM3 MAPT 2998/4885MEN1 2906/4885KMT2A 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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