Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382896 | 0.82 | ALDH1A1 (0.69) | KMT2AALDH1A1LMNANOD2KDM4E | |
| SCHEMBL4632948 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1LMNANOD2MEN1 | |
| SCHEMBL4632910 | 0.77 | KMT2A (0.52) | KMT2AALDH1A1LMNANOD2MAPT | |
| SCHEMBL4632959 | 0.76 | EDNRA (0.47) | KMT2AALDH1A1LMNANOD2KDM4E | |
| SCHEMBL4635043 | 0.76 | CXCR2 (0.55) | KMT2AALDH1A1LMNANOD2MEN1 | |
| SCHEMBL4633576 | 0.75 | KMT2A (0.50) | KMT2AALDH1A1LMNANOD2MEN1 | |
| SCHEMBL4633540 | 0.75 | CXCR2 (0.51) | KMT2AALDH1A1LMNANOD2MEN1 | |
| SCHEMBL4604930 | 0.75 | MAOB (0.47) | KMT2AALDH1A1LMNANOD2KDM4E | |
| SCHEMBL4632960 | 0.75 | LMNA (0.47) | KMT2AALDH1A1LMNANOD2MEN1 | |
| SCHEMBL4634993 | 0.74 | KMT2A (0.46) | KMT2AALDH1A1LMNANOD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |