Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632206 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL16011476 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL14010195 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL6832069 | 0.77 | KDM4E (0.75) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL29351326 | 0.77 | KDM4E (0.75) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL14010244 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1TDP1POLBLMNA | |
| Hydrochloric Acid SCHEMBL9773650 | 0.77 | KDM4E (0.74) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL16009022 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL30564254 | 0.76 | KDM4E (0.81) | KDM4EALDH1A1TDP1POLBLMNA | |
| SCHEMBL10695481 | 0.76 | ALDH1A1 (0.70) | KDM4EALDH1A1TDP1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139574-A1 | Novel quinoline derivatives | CADILA HEALTHCARE LIMITED | 2008-06-12 | — | — | US | disclosed |
| EP-1927589-A1 | Quinoline derivatives | CADILA HEALTHCARE LTD. (IN) | 2008-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139574-A1 | Novel quinoline derivatives | UGT1A7, CYP3A5, CYP3A7 | KDM4E 2801/4885ALDH1A1 1249/4885TDP1 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.