Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681090 | 0.88 | TYR (0.52) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL5385308 | 0.85 | ALDH1A1 (0.59) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL10586839 | 0.85 | TYR (0.59) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL5183011 | 0.84 | TYR (0.53) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL19304121 | 0.82 | HSD17B3 (0.41) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL4630314 | 0.81 | ALDH1A1 (0.50) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL30885859 | 0.81 | ALDH1A1 (0.50) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL27537800 | 0.81 | TYR (0.62) | TYRALDH1A1ALOX15HTTLMNA | |
| Benzene SCHEMBL28061142 | 0.81 | TYR (0.50) | TYRALDH1A1ALOX15HTTLMNA | |
| SCHEMBL2160202 | 0.80 | ALDH1A1 (0.70) | TYRALDH1A1ALOX15HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928945-A1 | THERMOPLASTIC POLYMER ADDITIVE COMPOSITONS | Colormatrix Europe, Ltd. (GB) | 2008-06-11 | — | — | EP | claimed |
| WO-2007039719-A1 | THERMOPLASTIC POLYMER ADDITIVE COMPOSITONS | COLORMATRIX EUROPE LIMITED (GB) | 2007-04-12 | — | — | WO | claimed |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2017-12-21 | — | — | US | disclosed |
| US-20160311805-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2016-10-27 | — | — | US | disclosed |
| US-20160108019-A1 | INHIBITORS OF KRAS G12C MUTANT PROTEINS | ARAXES PHARMA LLC | 2016-04-21 | — | — | US | disclosed |
| CN-102753628-A | Coating composition | BYK CHEMIE GMBH | 2012-10-24 | — | — | CN | disclosed |
| EP-1838821-A1 | LUBRICATING OIL COMPOSITION | Shell Internationale Research Maatschappij B.V. (NL) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006061436-A1 | LUBRICATING OIL COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108019-A1 | INHIBITORS OF KRAS G12C MUTANT PROTEINS | KRAS, NRAS, HRAS | TYR 3561/4885ALDH1A1 3457/4885ALOX15 4802/4885 |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | ESR1, ESRRA, ESR2 | TYR 1385/4885ALDH1A1 3275/4885ALOX15 2583/4885 |
| US-20160311805-A1 | ANTI-ESTROGENIC COMPOUNDS | ESR1, ESRRA, ESR2 | TYR 1385/4885ALDH1A1 3275/4885ALOX15 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.