SCHEMBL5385308

SCHEMBL5385308

CC(C)(C)c1cc(O)ccc1CO

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
TYR P14679 5/20 0.59
ALOX15 P16050 3/20 0.59
LMNA P02545 3/20 0.59
CYP2C9 P11712 3/20 0.59
NR1I2 O75469 1/20 0.59
MIF P14174 1/20 0.59
HTT P42858 1/20 0.59
NFE2L2 Q16236 1/20 0.59
HSD17B10 Q99714 1/20 0.59
KLF10 Q13118 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
CYP1A2 P05177 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
ATP2A2 P16615 1/20 0.41
ATP2A3 Q93084 1/20 0.41
GAA P10253 1/20 0.40
ACE2 Q9BYF1 1/20 0.39
HSPA5 P11021 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10586839 0.87 TYR (0.59) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL4634692 0.85 TYR (0.57) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL5183011 0.82 TYR (0.53) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL2160202 0.81 ALDH1A1 (0.70) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL4543641 0.80 ALDH1A1 (0.52) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL29054232 0.80 LMNA (0.52) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL30885859 0.79 ALDH1A1 (0.50) ALDH1A1TYRALOX15LMNACYP2C9
Benzene SCHEMBL28061142 0.79 TYR (0.50) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL7558821 0.79 TYR (0.50) ALDH1A1TYRALOX15LMNACYP2C9
SCHEMBL4630314 0.79 ALDH1A1 (0.50) ALDH1A1TYRALOX15LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618001-B1 Process for preparing active agents containing spherules RHONE POULENC NUTRITION ANIMAL (FR) 1997-08-13 EP claimed
US-5500415-A Process for the preparation of spherules of active principles and emulsions containing the spherules RHONE-POULENC NUTRITION ANIMALE (FR) 1996-03-19 US claimed
US-5492701-A ATOMIZING OIL IN WATER EMULSION CONTAINING VITAMIN A ACETATE OR VITAMIN E, ALLOWING THE SPHERULES FORMED TO FALL THROUGH COUNTERCURRENT COLD AIR FLOW(IN TOWER) INTO LIQUID CROSSLINKING AGENT, THEN RECOVERING HARDENED SPHERULES RHONE-POULENC NUTRITION ANIMALE (FR) 1996-02-20 US claimed
US-7202359-B2 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2007-04-10 US disclosed
CN-1234706-C Nitrogen-oxygen heterocyclic compound and preparation method thereof CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2006-01-04 CN disclosed
US-20050085634-A1 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2005-04-21 US disclosed
CN-1490318-A Nitrogen-oxygen heterocyclic compound and preparation method thereof 长春人造树脂厂股份有限公司 2004-04-21 CN disclosed
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-08 US disclosed
EP-1194487-A2 POLY(METH)ACRYLIC PHOTOCHROMIC COATING PPG Industries Ohio, Inc. (US) 2002-04-10 EP disclosed
US-6211328-B1 IN PRESENCE OF AN ACID GUN EI CHEMICAL INDUSTRY CO., LTD (JP) 2001-04-03 US disclosed
WO-2001002449-A2 POLY(METH)ACRYLIC PHOTOCHROMIC COATING PPG INDUSTRIES OHIO, INC. (US) 2001-01-11 WO disclosed
EP-0344733-A2 Novel antioxidant-peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same AOX1, KDM1A, BMI1 ALDH1A1 81/4885TYR 485/4885ALOX15 228/4885
US-20050085634-A1 Azaoxa heterocyclic compound and method of preparing the same AOX1, KDM1A, BMI1 ALDH1A1 116/4885TYR 314/4885ALOX15 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.