Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334637 | 0.85 | GRM5 (0.51) | GRM5 | |
| SCHEMBL4335240 | 0.77 | GRM5 (0.55) | GRM5 | |
| SCHEMBL4321267 | 0.75 | GRM5 (0.39) | GRM5 | |
| SCHEMBL4666475 | 0.70 | GRM5 (0.41) | GRM5 | |
| SCHEMBL4335199 | 0.69 | GRM5 (0.59) | GRM5 | |
| SCHEMBL31060423 | 0.67 | GRM5 (0.61) | GRM5 | |
| SCHEMBL13706986 | 0.65 | GRM5 (0.34) | GRM5 | |
| SCHEMBL6492190 | 0.63 | GRM5 (0.47) | GRM5 | |
| SCHEMBL22816393 | 0.60 | ADRA2A (0.42) | GRM5 | |
| SCHEMBL4329845 | 0.59 | GRM5 (0.61) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931635-A1 | TETRAHYDROQUINOLINONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Merz Pharma GmbH & Co.KGaA (DE) | 2008-06-18 | — | — | EP | claimed |
| WO-2007023290-A1 | TETRAHYDROQUINOLINONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-03-01 | — | — | WO | claimed |
| WO-2007023242-A1 | TETRAHYDROQUINOLINONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-03-01 | — | — | WO | claimed |